General Information of This Antibody-drug Conjugate (ID: DRG0YFPJB)
ADC Name
Oba01
Synonyms
Oba01; HYADC-Oba01
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Organization
Heyuan Adisis Biotech (Originator)
Drug Status
Phase 1
Drug-to-Antibody Ratio
4
Structure
Antibody Name
Zaptuzumab
 Antibody Info 
Antigen Name
Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B)
 Antigen Info 
Payload Name
Monomethyl auristatin E
 Payload Info 
Payload Target
Microtubule (MT)
 Target Info 
Linker Name
PY-MAA-Val-Cit-PABC
 Linker Info 
Conjugate Type
Reactive Cysteines
Combination Type
blivedotin
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Disease Name Phase 1 Phase 2 Phase 3 Approved
Lung cancer
1 Trials
Clinical trial identifier
NCT06083870; CTR20232785