Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ID: DRG0RBXQN)
| ADC Name |
YL242
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| Synonyms |
YL242
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| Organization |
MediLink Therapeutics (Originator)
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| Drug Status |
Phase 1/2
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| Drug-to-Antibody Ratio |
8
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| Structure |
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| Antibody Name |
Anti-VEGF antibody
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Antibody Info | ||||
| Antigen Name |
Vascular endothelial growth factor (VEGF)
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Antigen Info | ||||
| Payload Name |
YL0010014
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Payload Info | ||||
| Payload Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
VK*G-NHCH2-O linker
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Linker Info | ||||
| Conjugate Type |
Random Cysteines
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| Combination Type |
pelitecan
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2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
| Disease Name | Phase 1 | Phase 2 | Phase 3 | Approved |
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| Gastroesophageal junction adenocarcinoma | ||||
| Gastric cancer | ||||
| Colorectal cancer | ||||
| Lung cancer | ||||
| Unspecific solid tumor |