ADC Name	N297Q ADC
Synonyms	tubulysin-aMeso PEG ADC (N297Q ADC)    Click to Show/Hide
Organization	Bristol Myers Squibb.
Drug Status	Investigative
Drug-to-Antibody Ratio	3.3
	3D MOL			2D MOL
Antibody Name	Undisclosed
Antigen Name	Mesothelin (MSLN)					Antigen Info
Payload Name	Undisclosed
Linker Name	Undisclosed
Conjugate Type	Site-specific conjugation at N297Q.

Standard Type	Value	Units	Description	Reference
Maximum Observed Concentration (Cmax)	7229	ng/mL	PK parameters of three ADCs dosed at 0.5 mg/kg in vivo.	[1]
Area Under the Concentration-Time Curve (AUC)	1172	h·ug/mL	PK parameters of three ADCs dosed at 0.5 mg/kg in vivo, AUC0-336h.	[1]

Standard Type	Value	Units	Description	Reference
Elimination Half-Life (t1/2)	334	h	PK parameters of three ADCs dosed at 0.5 mg/kg in vivo.	[1]

Ref 1	The Impact of Conjugation Mode and Site on Tubulysin Antibody-Drug-Conjugate Efficacy and Stability