General Information of This Antibody-drug Conjugate (ID: DRG0IZSNN)
ADC Name
AZD4512
Synonyms
AZD4512
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Organization
AstraZeneca (Top20 MNC) (Originator)
Drug Status
Phase 1/2
Antibody Name
Anti-CD22 antibody
 Antibody Info 
Antigen Name
B-cell receptor CD22 (CD22)
 Antigen Info 
Payload Name
TOP1 inhibitor
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
A cleavable linker
 Linker Info 
Conjugate Type
Undisclosed
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Disease Name Phase 1 Phase 2 Phase 3 Approved
Unspecific non-hodgkin lymphoma
1 Trials
Clinical trial identifier
TWCT00005324; NCT07123454; jRCT2031250366; EUCT2025-522371-29-00
Acute lymphoblastic leukemia
1 Trials
Clinical trial identifier
TWCT00005329; NCT07109219; jRCT2031250707; EudraCT2025-522372-93; EUCT2025-522372-93-00