General Information of This Antibody-drug Conjugate (ID: DRG0GYMEE)
ADC Name
ESG406
Synonyms
ESG406
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Organization
Shanghai Escugen Biotechnology (Escugen) (Originator)
Drug Status
Phase 1
Antibody Name
Anti-TROP2 mAb
 Antibody Info 
Antigen Name
Tumor-associated calcium signal transducer 2 (TACSTD2)
 Antigen Info 
Payload Name
Exatecan
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
A cleavable linker
 Linker Info 
Conjugate Type
Undisclosed
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Disease Name Phase 1 Phase 2 Phase 3 Approved
Unspecific solid tumor
1 Trials
Clinical trial identifier
NCT06979674; CTR20251781