Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ID: DRG0ASYKZ)
| ADC Name |
Izeltabart tapatansine
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| Synonyms |
izeltabart tapatansine; IMGC936; IMGC936-0901
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| Organization |
ImmunoGen (Top20 MNC) (Originator);MacroGenics (Originator) (No Rights)
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| Drug Status |
Phase 1/2 (discontinued)
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| Drug-to-Antibody Ratio |
2
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| Structure |
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| Antibody Name |
Izeltabart
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Antibody Info | ||||
| Antigen Name |
Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9)
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Antigen Info | ||||
| Payload Name |
DM21-C
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Payload Info | ||||
| Payload Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mc-Ala-Ala-Ala
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Linker Info | ||||
| Conjugate Type |
Reactive Cysteines
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| Combination Type |
tapatansine
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2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
| Disease Name | Phase 1 | Phase 2 | Phase 3 | Approved |
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| Gastroesophageal junction adenocarcinoma | ||||
| Colorectal cancer | ||||
| Pancreatic cancer | ||||
| Lung cancer | ||||
| Breast cancer | ||||
| Unspecific solid tumor |