Antigen Information
General Information of This Antigen (ID: TAR0UTVLX)
| Antigen Name | Galectin-3-binding protein (LGALS3BP) |
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| Gene Name | LGALS3BP |
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| Gene ID | ||||||
| Synonym | M2BP; Basement membrane autoantigen p105;Lectin galactoside-binding soluble 3-binding protein;Mac-2-binding protein;Tumor-associated antigen 90K |
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| Sequence |
MTPPRLFWVWLLVAGTQGVNDGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASV
VCRALGFENATQALGRAAFGQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAG VVCTNETRSTHTLDLSRELSEALGQIFDSQRGCDLSISVNVQGEDALGFCGHTVILTANL EAQALWKEPGSNVTMSVDAECVPMVRDLLRYFYSRRIDITLSSVKCFHKLASAYGARQLQ GYCASLFAILLPQDPSFQMPLDLYAYAVATGDALLEKLCLQFLAWNFEALTQAEAWPSVP TDLLQLLLPRSDLAVPSELALLKAVDTWSWGERASHEEVEGLVEKIRFPMMLPEELFELQ FNLSLYWSHEALFQKKTLQALEFHTVPFQLLARYKGLNLTEDTYKPRIYTSPTWSAFVTD SSWSARKSQLVYQSRRGPLVKYSSDYFQAPSDYRYYPYQSFQTPQHPSFLFQDKRVSWSL VYLPTIQSCWNYGFSCSSDELPVLGLTKSGGSDRTIAYENKALMLCEGLFVADVTDFEGW KAAIPSALDTNSSKSTSSFPCPAGHFNGFRTVIRPFYLTNSSGVD Click to Show/Hide
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| Function |
Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.
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| Uniprot Entry | ||||||
| HGNC ID | ||||||
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Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
| The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens | ||||
|---|---|---|---|---|
Anti-LGALS3BP mAb 1959-sss
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
MP-1959-ADC
[1]
|
Maytansinoid |
Microtubule (MT) |
Undisclosed |
Undisclosed
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
1959-SSS-DM3
[2]
|
Maytansinoid DM3 |
Microtubule (MT) |
Undisclosed |
|
|
1959-sss/DM4
[3]
|
Mertansine DM4 |
Microtubule (MT) |
Undisclosed |
|
|
MP-LGS-ADC
[4]
|
Undisclosed |
Undisclosed |
Undisclosed |
References