Antigen Information

General Information of This Antigen (ID: TAR0LWLGS)
Antigen Name
Kidney-associated antigen 1 (KAAG1)
Gene Name
KAAG1
Gene ID
353219
Synonym
RU2AS; RU2 antisense gene protein
Sequence
MDDDAAPRVEGVPVAVHKHALHDGLRQVAGPGAAAAHLPRWPPPQLAASRREAPPLSQRP
HRTQGAGSPPETNEKLTNPQVKEK

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Uniprot Entry
KAAG1_HUMAN
HGNC ID
HGNC:21031
Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens
Anti-KAAG1 mAb AB-3A4
 Antibody Info 
ADC Name Payload Target Linker ADC Info
AB-3A4-Val-Cit-MMAE [1]
Monomethyl auristatin E
Microtubule (MT)
Mc-Val-Cit-PABC
 ADC Info 
Olintatug
 Antibody Info 
ADC Name Payload Target Linker ADC Info
Olintatug tesirine
SG3199 (SC-DR002)
Human deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala-PABC
 ADC Info 
References
Ref 1 AB-3A4: A novel KAAG1-targeting antibody-drug conjugate is active in models of ovarian carcinoma, triple-negative breast cancer and castration-resistant prostate cancer. Cancer Res (2014) 74 (19_Supplement): 666.