Antigen Information
General Information of This Antigen (ID: TAR0CYSHF)
| Antigen Name | Interleukin-2 receptor subunit alpha (IL2RA) |
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| Gene Name | IL2RA |
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| Gene ID | ||||||
| Synonym | TAC antigen;p55;CD25 |
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| Sequence |
MDSYLLMWGLLTFIMVPGCQAELCDDDPPEIPHATFKAMAYKEGTMLNCECKRGFRRIKS
GSLYMLCTGNSSHSSWDNQCQCTSSATRNTTKQVTPQPEEQKERKTTEMQSPMQPVDQAS LPGHCREPPPWENEATERIYHFVVGQMVYYQCVQGYRALHRGPAESVCKMTHGKTRWTQP QLICTGEMETSQFPGEEKPQASPEGRPESETSCLVTTTDFQIQTEMAATMETSIFTTEYQ VAVAGCVFLLISVLLLSGLTWQRRQRKSRRTI Click to Show/Hide
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| Function |
Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.
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Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
| The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens | ||||
|---|---|---|---|---|
A detuned-affinity anti-CD25 mAb
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
PF-08046032
[1]
|
Monomethyl auristatin E |
Microtubule (MT) |
Mc-Val-Cit-PABC |
Camidanlumab
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
Camidanlumab tesirine
|
SG3199 (SC-DR002) |
Human deoxyribonucleic acid (hDNA) |
Mal-PEG8-Val-Ala-PABC |
Undisclosed
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
RM-1995
|
IRDye 700DX |
Undisclosed |
Undisclosed |
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Anti-cancer therapy (Philogen/Pfizer)
[2]
|
Undisclosed |
Undisclosed |
Undisclosed |
References